[7], The macrophyte Myriophyllum spicatum produces ellagic acid. 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione, c1c2c3c4c(cc(c(c4oc2=O)O)O)c(=O)oc3c(c1O)O [14][15], Urolithins, such as urolithin A, are microflora human metabolites of dietary ellagic acid derivatives that are under study as anti-cancer agents. [3], Ellagic acid was first discovered by chemist Henri Braconnot in 1831.

ting biaryl. ; Target: CK2; Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. [5] Julius Löwe was the first person to synthesize ellagic acid by heating gallic acid with arsenic acid or silver oxide. CopyCopied, CSID:4445149, http://www.chemspider.com/Chemical-Structure.4445149.html (accessed 02:51, Nov 13, 2020) arcinogenic activity and also inhibits glutathione S-transferase.

Ellagic acid has been identified by the U.S. Food and Drug Administration as a "fake cancer 'cure'". Irritant/Light Sensitive/Store under Argon.

Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase. Ellagic Acid is a cell permeable and strong casein kinase 2 (CK2) inhibitor (Ki = 20 nM) which acts as a potent antioxidant and anti-mutagenic. [12], Ellagic acid has been marketed as a dietary supplement with a range of claimed benefits against cancer, heart disease, and other medical problems. Ellagic Acid is a cell permeable and strong casein kinase 2 (CK2) inhibitor (Ki = 20 nM) which acts as a potent antioxidant and anti-mutagenic.

Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase.

Plants produce ellagic acid from hydrolysis of tannins such as ellagitannin and geraniin.Ellagic acid has antiproliferative and antioxidant properties in a number of in vitro and small-animal models. Exhibits antioxidant, antitumor and antic [17], 2,3,7,8-Tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione, InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H, InChI=1/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H, Except where otherwise noted, data are given for materials in their, "The Formation of Ellagic Acid from Galloyl-Glycine by, "Protein glycation inhibitors from the fruiting body of, "Postharvest sensory and phenolic characterization of 'Elegant Lady' and 'Carson' peaches", "187 Fake Cancer 'Cures' Consumers Should Avoid", "Warning Letter sent to Millennium Health", "Warning Letter sent to Kenton Campbell at Prime Health Direct, Ltd", "Gastrointestinal microflora, food components and colon cancer prevention", Allopregnanedione (5α-dihydroprogesterone), https://en.wikipedia.org/w/index.php?title=Ellagic_acid&oldid=957891010, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 21 May 2020, at 00:29. Casein Kinase inhibitor;Carbonic anhydrase inhibitor;PKA inhibitor;PKC inhibitor;SMO inhibitor. Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk and FGR respectively). [4] He also suggested its formation from galloyl-glycine by Penicillium in 1915. Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk and FGR respectively).

Very slightly soluble in water. Combustible. CopyCopied, AFSDNFLWKVMVRB-UHFFFAOYSA-N

The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits, but it has been identified by the U.S. Food and Drug Administration as a fake cancer cure. Plants produce ellagic acid from hydrolysis of tannins such as ellagitannin and geraniin. The name comes from the French term acide ellagique, from the word galle spelled backwards[1] because it can be obtained from noix de galle (galls), and to distinguish it from acide gallique (gallic acid). Incompatible withstrong oxidizing agents. Ellagic acid is the dilactone of hexahydroxydiphenic acid.

CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:4775, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton. Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. CopyCopied, InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H Ellagic acid is an organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. [8], Ellagic acid can be found in the medicinal mushroom Phellinus linteus.

Enzyme; Metabolism; Cell Cycle/Checkpoint, Selective inhibitor of CK2. [2], Urolithins are microflora human metabolites of dietary ellagic acid derivatives. Stable. [10] It is also found in peaches[11] and pomegranates.

[16] Claims that ellagic acid can treat or prevent cancer in humans have not been proven.

;Target: CK2Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables.

Also inhibits glutathione S-transferase. [9], The highest levels of ellagic acid are found in raw chestnuts, walnuts, pecans, cranberries, raspberries, strawberries, and grapes, as well as distilled beverages. Ellagic acid is the dilactone of hexahydroxydiphenic acid.

Ellagic Acid is a cell permeable and strong casein kinase 2 (CK2) inhibitor (Ki = 20 nM) which acts as a potent antioxidant and anti-mutagenic. The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits, but it has been identified by the U.S. Food and Drug Administration as a fake cancer cure. [4][6], Ellagic acid is found in oak species such as the North American white oak (Quercus alba) and European red oak (Quercus robur). An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resul It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.

[13] A number of U.S.-based sellers of dietary supplements have received Warning Letters from the Food and Drug Administration for promoting ellagic acid with claims that violate the Federal Food, Drug, and Cosmetic Act. Structure, properties, spectra, suppliers and links for: Ellagic acid, 476-66-4. As with other polyphenol antioxidants, ellagic acid has a chemoprotective effect in cellular models by reducing oxidative stress.

WARNING: Irreversible damage risk, protect skin/eyes/lungs. The antiproliferative and antioxidant properties of ellagic acid have spurred preliminary research into the potential health benefits of ellagic acid consumption. [4] Maximilian Nierenstein prepared this substance from algarobilla, dividivi, oak bark, pomegranate, myrabolams, and valonea in 1905.

Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk and FGR respectively). Ellagic acid is the dilactone of hexahydroxydiphenic acid. The antiproliferative properties of ellagic acid may be due to its ability to directly inhibit the DNA binding of certain carcinogens, including nitrosamines and polycyclic aromatic hydrocarbons. Soluble in 1 N NaOH (10mg/mL). Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables.



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